Horse antithymocyte globulin as salvage therapy after rabbit antithymocyte globulin for severe aplastic anemia.

Abstract

The effectiveness of salvage therapy for aplastic anemia patients unresponsive to initial rabbit antithymocyte globulin (r-ATG) or cyclophosphamide is not known. We investigated the administration of standard horse ATG (h-ATG) plus cyclosporine (CsA) in patients who were refractory to initial r-ATG/CsA (n = 19) or cyclophosphamide/CsA (n = 6) (registered at… (More)
DOI: 10.1002/ajh.23669

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