Hormones and Receptors in Endometrial Cancer

  title={Hormones and Receptors in Endometrial Cancer},
  author={David Bender and Thomas E. Buekers and Kimberly K. Leslie},
The uterine endometrium is exquisitely sensitive to hormones, in particular estrogen and progesterone and to a lesser extent androgens and glucocorticoids. These hormones tightly regulate the complex functioning of the female reproductive tract and are intimately involved in controlling the growth, development, and remodeling of reproductive tissues as well as the cyclic changes that occur during the menstrual cycle. Steroids function by binding to nuclear receptor proteins that act as… CONTINUE READING
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