Hormone replacement therapy and the association with coronary heart disease and overall mortality: Clinical application of the timing hypothesis

@article{Hodis2014HormoneRT,
  title={Hormone replacement therapy and the association with coronary heart disease and overall mortality: Clinical application of the timing hypothesis},
  author={H. Hodis and W. Mack},
  journal={The Journal of Steroid Biochemistry and Molecular Biology},
  year={2014},
  volume={142},
  pages={68-75}
}
  • H. Hodis, W. Mack
  • Published 2014
  • Medicine
  • The Journal of Steroid Biochemistry and Molecular Biology
Conclusions from randomized controlled trial (RCT) data over the past 10 years has spanned from presumed harm to consistency with observational data that hormone replacement therapy (HRT) decreases the risk for coronary heart disease (CHD) as well as overall mortality in women who are recently postmenopausal. Multiple clinical studies including randomized trials and observational studies converge with animal experimentation to show a consistency that HRT decreases CHD risk and overall mortality… Expand
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