Hormone replacement therapy and risk of breast cancer: the role of progestins

@article{Stahlberg2003HormoneRT,
  title={Hormone replacement therapy and risk of breast cancer: the role of progestins},
  author={Claudia Irene Stahlberg and Anette T{\o}nnes Pedersen and Elsebeth Lynge and Bent S. Ottesen},
  journal={Acta Obstetricia et Gynecologica Scandinavica},
  year={2003},
  volume={82}
}
Epidemiological studies have shown an increased risk of breast cancer associated with the use of hormone replacement therapy (HRT). This notion is mostly based on studies from the USA. During the last decades unopposed estrogen treatment has been used to a lesser extent, whereas the combined estrogen‐progestin treatment regimen is now prescribed worldwide. In the USA the predominant compounds are conjugated estrogens and medroxyprogesterone‐acetate, whereas oestradiol combined with testosterone… 

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