Hormone replacement therapy and physical function in healthy older men. Time to talk hormones?

@article{Giannoulis2012HormoneRT,
  title={Hormone replacement therapy and physical function in healthy older men. Time to talk hormones?},
  author={Manthos G Giannoulis and Finbarr C. Martin and K. Sreekumaran Nair and A. Margot Umpleby and Peter H Sőnksen},
  journal={Endocrine reviews},
  year={2012},
  volume={33 3},
  pages={314-77}
}
Improving physical function and mobility in a continuously expanding elderly population emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal exercise capacity are major determinants of physical function, and all decline with aging. This contributes to the incidence of frailty and disability observed in older men. Furthermore, it facilitates the accumulation of body fat and development of insulin resistance. Muscle adaptation to exercise is strongly influenced… CONTINUE READING
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