Hormone-Induced Protection Against Breast Cancer

  title={Hormone-Induced Protection Against Breast Cancer},
  author={Lakshmi Sivaraman and D. Medina},
  journal={Journal of Mammary Gland Biology and Neoplasia},
Reproductive history is a consistent risk factor for human breast cancer. Epidemiological studies have repeatedly demonstrated that early age of first full-term pregnancy is a strong protective factor against breast cancer and provides a physiologically operative model to achieve a practical mode of prevention. In rodents, the effects of full-term pregnancy can be mimicked by exposure to low doses of estrogen and progesterone or treatment with human chorionic gonadotropin. The cellular and… CONTINUE READING


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