Hormonal therapy in prostatic carcinoma.

  title={Hormonal therapy in prostatic carcinoma.},
  author={Martin I. Resnick},
  volume={24 5 Suppl},
A significant number of patients with newly diagnosed prostatic cancer will be found to have metastatic disease at time of presentation. Since the work of Huggins and Hodges in the early 1940s, endocrine manipulation and androgen deprivation have become the accepted methods of treating this group of patients. Approximately 70 per cent to 80 per cent of patients demonstrate positive clinical response. Many experience a decrease in the size of the primary tumor, a decrease in the levels of serum… CONTINUE READING