Hormonal regulation of the polarized function and distribution of Na/H exchange and Na/HCO3 cotransport in cultured mammary epithelial cells

@article{Sjaastad1993HormonalRO,
  title={Hormonal regulation of the polarized function and distribution of Na/H exchange and Na/HCO3 cotransport in cultured mammary epithelial cells},
  author={Michael D. Sjaastad and K S Zettl and G. Parry and Gary L. Firestone and Terry E. Machen},
  journal={The Journal of Cell Biology},
  year={1993},
  volume={122},
  pages={589 - 600}
}
The time course for development of polarized function and morphological distribution of pH regulatory mechanisms has been examined in a mouse mammary epithelial cell line (31EG4). Monolayers grown on permeable supports had tight junctions when grown 3-4 days in the presence of the lactogenic hormones dexamethasone (D, a synthetic glucocorticoid) and insulin… CONTINUE READING