Hormonal regulation of the peripubertal surge of insulin-like growth factor-I in the rat.

@article{Handelsman1987HormonalRO,
  title={Hormonal regulation of the peripubertal surge of insulin-like growth factor-I in the rat.},
  author={David J Handelsman and Jennifer A Spaliviero and Carolyn D. Scott and Robert C. Baxter},
  journal={Endocrinology},
  year={1987},
  volume={120 2},
  pages={491-6}
}
The marked increase in circulating insulin-like growth factor-I (IGF-I) levels during puberty observed in primates indicates an important functional relationship between hypothalamic-pituitary gonadal function and hormonal regulation of peripubertal circulating IGF-I levels. Recent studies demonstrating local production and secretion of gonadal peptides… CONTINUE READING