Hormonal regulation of hepatic IGF-I and IGF-II gene expression in the marine teleost Sparus aurata.

@article{Carnevali2005HormonalRO,
  title={Hormonal regulation of hepatic IGF-I and IGF-II gene expression in the marine teleost Sparus aurata.},
  author={Oliana Carnevali and Marco Cardinali and Francesca Maradonna and Marco Parisi and Ike Olivotto and Alberta Maria Polzonetti-Magni and Gilberto Mosconi and Bruria Funkenstein},
  journal={Molecular reproduction and development},
  year={2005},
  volume={71 1},
  pages={12-8}
}
The present work aimed to determine whether GnRH potentiates the effect of growth hormone (GH) on insulin-like growth factors (IGF-I and IGF-II) hepatic gene expression in Sparus aurata liver. Since several hepatic genes were shown to underlie direct regulation via the hepatic estrogen receptor, another aim was to extend our understanding of direct estrogen effects on liver IGFs gene expression. Pre-reproductive sea bream females were treated with GH, GnRH, estradiol-17beta, GH plus GnRH, and… CONTINUE READING

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