Hormonal regulation of gonadotropin receptor mRNA in rat ovary during follicular growth and luteinization.

@article{Nakamura1991HormonalRO,
  title={Hormonal regulation of gonadotropin receptor mRNA in rat ovary during follicular growth and luteinization.},
  author={Kayoko Nakamura and Takashi Minegishi and Yoshinobu Takakura and Kaoru Miyamoto and Yoshihisa Hasegawa and Yoshito Ibuki and Miki Igarashi},
  journal={Molecular and cellular endocrinology},
  year={1991},
  volume={82 2-3},
  pages={259-63}
}
To investigate the regulation of the follicle-stimulating hormone (FSH) and luteinizing hormone/human chorionic gonadotropin (LH/hCG) receptor genes by gonadotropins, we examined the effect of pregnant mare's serum gonadotropin (PMSG) or PMSG-hCG on the expression of FSH and LH/hCG receptors in rat ovaries. After administration of PMSG, Northern blot analysis using the FSH receptor cDNA probe revealed that a major band of 2400 nucleotides was detected which reached the maximal level on day 3… CONTINUE READING