Hormonal regulation of glycolytic enzyme gene and pyruvate dehydrogenase kinase/phosphatase gene transcription.

@article{Wang2009HormonalRO,
  title={Hormonal regulation of glycolytic enzyme gene and pyruvate dehydrogenase kinase/phosphatase gene transcription.},
  author={Zhe Wang and Yasumasa Iwasaki and Li Feng Zhao and Mitsuru Nishiyama and Takafumi Taguchi and Makoto Tsugita and Machiko Kambayashi and Kozo Hashimoto and Yoshio Terada},
  journal={Endocrine journal},
  year={2009},
  volume={56 8},
  pages={1019-30}
}
Both glucocorticoid and insulin are known to have an anabolic effect on lipogenesis. The glycolytic pathway is a part of the lipogenic pathway in the liver, and glycolytic enzymes mediate the conversion from glucose to pyruvate, and pyruvate dehydrogenase complex (PDC) mediates the conversion from pyruvate to acetyl-CoA, the activity of which is regulated… CONTINUE READING