Hormonal modulation of glomerular function.

  title={Hormonal modulation of glomerular function.},
  author={Lance D. Dworkin and Iekuni Ichikawa and Barry M. Brenner},
  journal={The American journal of physiology},
  volume={244 2},
Glomeruli contain receptors for many hormones. Binding of angiotensin II (ANG II) or antidiuretic hormone (ADH) to glomerular mesangial cells elicits a contractile response. Other hormones induce synthesis of cyclic nucleotides (cAMP, cGMP). Glomeruli also synthesize several prostaglandins, renin, and ANG II. Micropuncture studies in Munich-Wistar rats have examined the effects of vasoactive drugs and hormones on the filtration process. Several vasodilators increase renal plasma flow in the dog… CONTINUE READING


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