Hormonal management of migraine at menopause

@article{Nappi2009HormonalMO,
  title={Hormonal management of migraine at menopause},
  author={Rossella Elena Nappi and Grazia Sances and Silvia Detaddei and Alessandra Ornati and Luca Chiovato and Franco Polatti},
  journal={Menopause International},
  year={2009},
  volume={15},
  pages={82 - 86}
}
In this review, we underline the importance of linking migraine to reproductive stages for optimal management of such a common disease across the lifespan of women. Menopause has a variable effect on migraine depending on individual vulnerability to neuroendocrine changes induced by estrogen fluctuations and on the length of menopausal transition. Indeed, an association between estrogen ‘milieu’ and attacks of migraine is strongly supported by several lines of evidence. During the perimenopause… 

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