Hormonal control of messenger ribonucleic acid metabolism in barley aleurone layers.


Ribonucleic acid containing poly(adenylic acid) [poly(A)-RNA] is present in barley aleurone layers. This poly(A)-RNA becomes labeled with radioactive precursors of RNA during the incubation of isolated aleurone layers with or without gibberellic acid. However, the rate of synthesis of poly(A)-RNA is enhanced by gibberellic acid. This enhancement begins within 3-4 hr of addition of the hormone and reaches a maximum, which is about 50-60% over the control, 10-12 hr after addition of the hormone. Cordycepin inhibits total RNA as well as poly(A)-RNA synthesis in barley aleurone layers. However, cordycepin inhibits the hormone-controlled synthesis of alpha-amylase (EC only if it is added 12 hr or less after gibberellic acid. The insensitivity of alpha-amylase production to cordycepin after 12 hr of gibberellic acid treatment suggests that alpha-amylase is translated from stable messenger RNA.

7 Figures and Tables


Citations per Year

381 Citations

Semantic Scholar estimates that this publication has 381 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Ho1974HormonalCO, title={Hormonal control of messenger ribonucleic acid metabolism in barley aleurone layers.}, author={David T. Ho and Joseph E. Varner}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1974}, volume={71 12}, pages={4783-6} }