Hormonal control of chloride secretion by canine tracheal epithelium: an electrophysiologic analysis.

@article{Frizzell1981HormonalCO,
  title={Hormonal control of chloride secretion by canine tracheal epithelium: an electrophysiologic analysis.},
  author={Raymond A Frizzell and Michael J. Welsh and Philip L. Smith},
  journal={Annals of the New York Academy of Sciences},
  year={1981},
  volume={372},
  pages={558-70}
}
A principal event in the stimulation of cyclic AMP-induced active C1 secretion across canine tracheal epithelium is an increase in the C1 permeability of the apical cell membrane. This permits C1 to leave the cell down its electrochemical potential difference across this barrier. C1 transport across the basolateral membrane appears to be nonconductive and may be mediated by NaC1 cotransport. Increased C1 entry across the basolateral membrane would enhance Na entry into the cell and secondarily… CONTINUE READING

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