Hormonal contraceptive use, herpes simplex virus infection, and risk of HIV-1 acquisition among Kenyan women.

@article{Baeten2007HormonalCU,
  title={Hormonal contraceptive use, herpes simplex virus infection, and risk of HIV-1 acquisition among Kenyan women.},
  author={Jared M Baeten and Sarah F Benki and Vrasha Chohan and Ludo Lavreys and R Scott McClelland and Kishorchandra N. Mandaliya and Jeckoniah O. Ndinya-Achola and Walter G. Jaoko and Julie M Overbaugh},
  journal={AIDS},
  year={2007},
  volume={21 13},
  pages={1771-7}
}
BACKGROUND Studies of the effect of hormonal contraceptive use on the risk of HIV-1 acquisition have generated conflicting results. A recent study from Uganda and Zimbabwe found that women using hormonal contraception were at increased risk for HIV-1 if they were seronegative for herpes simplex virus type 2 (HSV-2), but not if they were HSV-2 seropositive. OBJECTIVE To explore the effect of HSV-2 infection on the relationship between hormonal contraception and HIV-1 in a high-risk population… CONTINUE READING