Hormonal contraception and chemoprevention of female cancers.

  title={Hormonal contraception and chemoprevention of female cancers.},
  author={Malcolm C. Pike and Darcy V. Spicer},
  journal={Endocrine-related cancer},
  volume={7 2},
Oral contraceptive (OC) use significantly reduces the risk of endometrial and ovarian cancer, has only a minimal effect on breast cancer, but may increase the risk of cervical cancer. These effects can be readily explained in terms of the effects of OCs on cell proliferation in these tissues. This analysis suggests how a hormonal contraceptive based on a GnRH agonist plus low-dose add-back sex steroids could be made that would greatly reduce lifetime risk of breast and ovarian cancer. Such a… CONTINUE READING


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