Hormonal characterization of female SL/Ni mice: a small thymus gland strain exhibiting ovarian dysgenesis.

@article{Michael1988HormonalCO,
  title={Hormonal characterization of female SL/Ni mice: a small thymus gland strain exhibiting ovarian dysgenesis.},
  author={Sandra D. Michael and Osamu Taguchi and Yasuaki Nishizuka},
  journal={Journal of reproductive immunology},
  year={1988},
  volume={12 4},
  pages={277-86}
}
Female SL/Ni mice have a small thymus gland and show accelerated aging of the reproductive system characterized by an early loss of the follicular apparatus and early onset of ovarian tumors. At 9 months of age, circulating levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) were higher in the SL/Ni animals than in controls while prolactin (PRL) was lower in the SL/Ni mice. The trends of these hormones are consistent with the loss of the follicular apparatus which is… CONTINUE READING

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