Hormonal and reproductive risk factors for development of systemic lupus erythematosus: results of a population-based, case-control study.

Abstract

OBJECTIVE Estrogen and prolactin may accelerate the progression of murine systemic lupus erythematosus (SLE). In humans, 85% of lupus patients are women, which also suggests the importance of hormonal factors in disease pathogenesis. The purpose of this study was to examine hormonal and reproductive risk factors for lupus among women. METHODS This… (More)

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@article{Cooper2002HormonalAR, title={Hormonal and reproductive risk factors for development of systemic lupus erythematosus: results of a population-based, case-control study.}, author={G. S. Cooper and Mary Anne Dooley and Edward L. Treadwell and E William St Clair and Gary S. Gilkeson}, journal={Arthritis and rheumatism}, year={2002}, volume={46 7}, pages={1830-9} }