Hormonal and metabolic effects of olanzapine and clozapine related to body weight in rodents.

@article{Albaugh2006HormonalAM,
  title={Hormonal and metabolic effects of olanzapine and clozapine related to body weight in rodents.},
  author={Vance L Albaugh and Cathy Renee Henry and Nicholas T. Bello and Andr{\'a}s S{\'a}ndor Hajnal and Susan L Lynch and Beth Halle and Christopher J. Lynch},
  journal={Obesity},
  year={2006},
  volume={14 1},
  pages={36-51}
}
OBJECTIVE To characterize a model of atypical antipsychotic drug-induced obesity and evaluate its mechanism. RESEARCH METHODS AND PROCEDURES Chronically, olanzapine or clozapine was self-administered via cookie dough to rodents (Sprague-Dawley or Wistar rats; C57Bl/6J or A/J mice). Chronic studies measured food intake, body weight, adiponectin, active ghrelin, leptin, insulin, tissue wet weights, glucose, clinical chemistry endpoints, and brain dopaminergic D2 receptor density. Acute studies… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 69 extracted citations

Similar Papers

Loading similar papers…