Hormonal alterations following seizures

@article{Luef2010HormonalAF,
  title={Hormonal alterations following seizures},
  author={Gerhard J. Luef},
  journal={Epilepsy \& Behavior},
  year={2010},
  volume={19},
  pages={131-133}
}
  • G. Luef
  • Published 1 October 2010
  • Medicine, Biology
  • Epilepsy & Behavior
Hormonal consequences of epilepsy and its treatment in men
TLDR
Testosterone and sexual function appear not to be affected by the newer generation (noninducing) anticonvulsants, and further study is needed to clarify the precise mechanisms behind these alterations, as some of the data conflict.
Seizure duration may increase thyroid-stimulating hormone levels in children experiencing a seizure
TLDR
Neuronal excitability by seizure can cause thyroid hormonal changes, which likely reflects changes in hypothalamic function.
Serum prolactin levels in diff erential diagnosis of pediatric epileptic and nonepileptic ( pseudo-SEIZURES ) seizures
TLDR
Serum prolactin level in the postictal period had an important role in diff erentiating nonepileptic cases such as breath holding spells, night terror and hysterical conversions from epileptic seizures and syncope, but there was no signifi cant diff erence between serum Prolactin levels.
General seizures revealing macro-adenomas secreting prolactin or prolactin and growth hormone in men
TLDR
Epilepsy, which is a life-threatening condition, can be the first presentation in men with prolactinomas or somatolactotroph adenomas, especially those involving the supra sellar area, and the brain.
Reproductive health in patients with epilepsy
THE HORMONAL CHANGES AMONG NIGERIAN WOMEN WITH EPILEPSY
TLDR
WWE had lower progesterone, lower FSH and more menstrual abnormalities, compare to controls in the population, and there was no difference with use of AEDs.
Hemogram parameters in epilepsy may be indicators of chronic inflammation and hypoxemia
TLDR
White blood cell, neutrophil, and lymphocyte levels were significantly higher during seizures compared with seizure-free periods in patients with epilepsy, and mean corpuscular volume, mean platelet volume, and red blood cell distribution width values compared with the controls.
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Based on the findings in 17 patients investigated by means of intracranial electrodes, it was not able to establish different criteria for different focus localisations: in 66% of both temporal as well as frontal lobe seizures the 700 μU/ml level was exceeded.
Interictal and postictal alterations of pulsatile secretions of luteinizing hormone in temporal lobe epilepsy in men
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Altered timing and regularity of neuroendocrine pulse patterns may underlie other disorders of homeostasis in mesial temporal lobe epilepsy.
Abnormal pulsatile secretion of luteinizing hormone in men with epilepsy
TLDR
The relationship of pulse frequency to the nature and laterality of paroxysmal discharges makes it unlikely that endocrine abnormalities can be attributed to medication alone and strengthens the notion that temporal lobe epileptiform discharges may disrupt hypothalamic regulation of pituitary secretion.
Interictal EEG discharges, reproductive hormones, and menstrual disorders in epilepsy
TLDR
The findings indicate that reproductive endocrine function differs between women with epilepsy and normal control subjects, which is consistent with the finding that different reproductive disorders may develop in relation to left‐ and right‐sided temporolimbic epilepsy.
Reproductive Endocrine Disorders in Women with Primary Generalized Epilepsy
TLDR
The hormonal alterations observed in the patients with normal menstrual cycles seem to support the hypothesis that a neurotransmitter dysfunction might be the common pathogenetic mechanism resulting in both REDs and PGE.
Use of serum prolactin in diagnosing epileptic seizures
TLDR
Elevated serum prolactin assay, when measured in the appropriate clinical setting at 10 to 20 minutes after a suspected event, is a useful adjunct for the differentiation of generalized tonic–clonic or complex partial seizure from psychogenic nonepileptic seizure among adults and older children.
Serum prolactin and cortisol concentrations after grand mal seizures.
TLDR
Significant increase in both prolactin and cortisol levels occurred after seizures, which probably indicates an alteration in hypothalamic neurotransmitter activity during the seizure in patients with epilepsy.
Epilepsy and hormones: A critical review
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TLDR
Findings suggest that hypothalamic-pituitary control of gonadotropin secretion may be altered among patients with temporal lobe epilepsy.
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