Corpus ID: 32667298

Hormonal (gastrin, secretin, cholecystokinin) and secretory effects of bombesin and duodenal acidification in dogs.

@article{Miyata1980HormonalS,
  title={Hormonal (gastrin, secretin, cholecystokinin) and secretory effects of bombesin and duodenal acidification in dogs.},
  author={Masahiko Miyata and Phillip L. Rayford and J. C. Thompson},
  journal={Surgery},
  year={1980},
  volume={87 2},
  pages={
          209-15
        }
}
We have studied the influences of duodenal acidification on the effects of bombesin on gastric and pancreatic secretion and on blood levels of gastrin, secretin, and cholecystokinin (CCK) in six conscious dogs with chronic gastric and pancreatic fistulas. Duodenal acidification suppressed bombesin-stimulated gastric acid output (from 20.1 +/- 4.2 to 8.2 +/- 1.9 mEq/120 min) and gastrin release (from an integrated 2-hour output of 16.0 +/- 1.2 to 11.1 +/- 1.1 ng-min/ml). On the other hand… Expand
Pancreatic exocrine secretion. Release of gastrin and cholecystokinin in response to bombesin in pigs.
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It is concluded that the effects of exogenously administered bombesin on the exocrine pancreas in the rat are not mediated via release of endogenous cholecystokinin. Expand
In Vivo Action of Bombesin on Exocrine Pancreatic Secretion in the Rat: Independent of Cholecystokinin and Cholinergic Mediation
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