Hormetins, antioxidants and prooxidants: defining quercetin-, caffeic acid- and rosmarinic acid-mediated life extension in C. elegans

@article{Pietsch2011HormetinsAA,
  title={Hormetins, antioxidants and prooxidants: defining quercetin-, caffeic acid- and rosmarinic acid-mediated life extension in C. elegans},
  author={Kerstin Pietsch and Nadine Saul and Shumon Chakrabarti and Stephen R. St{\"u}rzenbaum and Ralph Menzel and Christian E. W. Steinberg},
  journal={Biogerontology},
  year={2011},
  volume={12},
  pages={329-347}
}
Quercetin, Caffeic- and Rosmarinic acid exposure extend lifespan in Caenorhabditis elegans. This comparative study uncovers basic common and contrasting underlying mechanisms: For all three compounds, life extension was characterized by hormetic dose response curves, but hsp-level expression was variable. Quercetin and Rosmarinic acid both suppressed bacterial growth; however, antibacterial properties were not the dominant reason for life extension. Exposure to Quercetin, Caffeic- and… CONTINUE READING
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