Hormesis and Its Place in Nonmonotonic Dose–Response Relationships: Some Scientific Reality Checks

@inproceedings{Mushak2007HormesisAI,
  title={Hormesis and Its Place in Nonmonotonic Dose–Response Relationships: Some Scientific Reality Checks},
  author={Paul Mushak},
  booktitle={Environmental health perspectives},
  year={2007}
}
  • Paul Mushak
  • Published 2007 in Environmental health perspectives
OBJECTIVE This analysis is a critical assessment of current hormesis literature. I discuss definitions, characterization, generalizability, mechanisms, absence of empirical data specific for hormesis hypothesis testing, and arguments that hormesis be the "default assumption" in risk assessment. DATA SOURCES Hormesis, a biological phenomenon typically described as low-dose stimulation from substances producing higher-dose inhibition, has recently garnered interest in several quarters. The… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

A perspective on the scientific, philosophical, and policy dimensions of hormesis.

Dose-response : a publication of International Hormesis Society • 2009
View 11 Excerpts
Highly Influenced

Hormesis in Regulatory risk assessment - Science and Science Policy.

Dose-response : a publication of International Hormesis Society • 2011
View 5 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 63 references

Effect of exposure to aromatic hydrocarbons on neurodevelopment in the first three years of life among inner city children

JA Pickrell, FW Oehme
2006

Increased mortality from lung cancer and bronchiectasis in young adults following exposure to arsenic in utero and early childhood

KA Thayer, R Melnick, K Burns, D Davis, J Huff
2006

The importance of hormesis to public health

K Crump
Environ Health Perspect • 2006

A critique of the use of hormesis in risk assessment

RJ Kociba, DG Keyes, JE Beyer, RM Carreon, CE Wade
Hum Exp Toxicol • 2005

Occurrence of hormetic dose responses in the toxicological literature , the hormetic data base : an overview

EJ Calabrese, R Cook
Toxicol Appl Pharmacol • 2005
View 1 Excerpt

Similar Papers

Loading similar papers…