Horizontally acquired divergent O-antigen contributes to escape from cross-immunity in the classical bordetellae

@inproceedings{Hester2013HorizontallyAD,
  title={Horizontally acquired divergent O-antigen contributes to escape from cross-immunity in the classical bordetellae},
  author={Sara E. Hester and Jihye Park and Laura L. Goodfield and Heather A. Feaga and Andrew Preston and Eric T. Harvill},
  booktitle={BMC Evolutionary Biology},
  year={2013}
}
Horizontal gene transfer (HGT) allows for rapid spread of genetic material between species, increasing genetic and phenotypic diversity. Although HGT contributes to adaptation and is widespread in many bacteria, others show little HGT. This study builds on previous work to analyze the evolutionary mechanisms contributing to variation within the locus encoding a prominent antigen of the classical bordetellae. We observed amongst classical bordetellae discrete regions of the lipopolysaccharide O… CONTINUE READING