Horizontally Transferred Genetic Elements and Their Role in Pathogenesis of Bacterial Disease

@article{Gyles2014HorizontallyTG,
  title={Horizontally Transferred Genetic Elements and Their Role in Pathogenesis of Bacterial Disease},
  author={C. Gyles and P. Boerlin},
  journal={Veterinary Pathology},
  year={2014},
  volume={51},
  pages={328 - 340}
}
  • C. Gyles, P. Boerlin
  • Published 2014
  • Biology, Medicine
  • Veterinary Pathology
  • This article reviews the roles that laterally transferred genes (LTG) play in the virulence of bacterial pathogens. The features of LTG that allow them to be recognized in bacterial genomes are described, and the mechanisms by which LTG are transferred between and within bacteria are reviewed. Genes on plasmids, integrative and conjugative elements, prophages, and pathogenicity islands are highlighted. Virulence genes that are frequently laterally transferred include genes for bacterial… CONTINUE READING
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