Horizontal transfer of mitochondria between mammalian cells: beyond co-culture approaches.

  title={Horizontal transfer of mitochondria between mammalian cells: beyond co-culture approaches.},
  author={Michael V Berridge and Melanie Jane McConnell and Carole H Grasso and Martina Bajzikova and Jaromira Kovarova and Jiri Neuzil},
  journal={Current opinion in genetics & development},
Current dogma holds that genes are the property of individual mammalian cells and partition between daughter cells during cell division. However, and rather unexpectedly, recent research has demonstrated horizontal cell-to-cell transfer of mitochondria and mitochondrial DNA in several mammalian cell culture systems. Furthermore, unequivocal evidence that mitochondrial DNA transfer occurs in vivo has now been published. While these studies show horizontal transfer of mitochondrial DNA in… CONTINUE READING
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