Horizontal gene transfer contributes to the wide distribution and evolution of type II restriction-modification systems

@article{Jeltsch2005HorizontalGT,
  title={Horizontal gene transfer contributes to the wide distribution and evolution of type II restriction-modification systems},
  author={Albert Jeltsch and Alfred Pingoud},
  journal={Journal of Molecular Evolution},
  year={2005},
  volume={42},
  pages={91-96}
}
Restriction modification (RM) systems serve to protect bacteria against bacteriophages. They comprise a restriction endonuclease activity that specifically cleaves DNA and a corresponding methyltransferase activity that specifically methylates the DNA, thereby protecting it from cleavage. Such systems are very common in bacteria. To find out whether the widespread distribution of RM systems is due to horizontal gene transfer, we have compared the codon usages of 29 type II RM systems with the… 
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