Horizontal Gene Transfer Regulation in Bacteria as a “Spandrel” of DNA Repair Mechanisms

  title={Horizontal Gene Transfer Regulation in Bacteria as a “Spandrel” of DNA Repair Mechanisms},
  author={Saliou Fall and Anne Mercier and Franck Bertolla and Alexandra Calteau and Laurent Gueguen and Guy Perri{\`e}re and Timothy M. Vogel and Pascal Simonet},
  journal={PLoS ONE},
  pages={760 - 766}
Horizontal gene transfer (HGT) is recognized as the major force for bacterial genome evolution. Yet, numerous questions remain about the transferred genes, their function, quantity and frequency. The extent to which genetic transformation by exogenous DNA has occurred over evolutionary time was initially addressed by an in silico approach using the complete genome sequence of the Ralstonia solanacearum GMI1000 strain. Methods based on phylogenetic reconstruction of prokaryote homologous genes… CONTINUE READING
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