Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development

@inproceedings{Baenke2013HookedOF,
  title={Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development},
  author={Franziska Baenke and Barrie Peck and Heike Miess and Almut Schulze},
  booktitle={Disease models & mechanisms},
  year={2013}
}
An increased rate of lipid synthesis in cancerous tissues has long been recognised as an important aspect of the rewired metabolism of transformed cells. However, the contribution of lipids to cellular transformation, tumour development and tumour progression, as well as their potential role in facilitating the spread of cancerous cells to secondary sites, are not yet fully understood. In this article, we review the recent findings that support the importance of lipid synthesis and metabolism… CONTINUE READING
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