Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development

  title={Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development},
  author={Franziska Baenke and Barrie Peck and Heike Miess and Almut Schulze},
  booktitle={Disease models & mechanisms},
An increased rate of lipid synthesis in cancerous tissues has long been recognised as an important aspect of the rewired metabolism of transformed cells. However, the contribution of lipids to cellular transformation, tumour development and tumour progression, as well as their potential role in facilitating the spread of cancerous cells to secondary sites, are not yet fully understood. In this article, we review the recent findings that support the importance of lipid synthesis and metabolism… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 126 extracted citations


Publications referenced by this paper.
Showing 1-10 of 114 references

G proteincoupled estrogen receptor mediates the up-regulation of fatty acid synthase induced by 17β-estradiol in cancer cells and cancer-associated fibroblasts

  • M. F. Santolla, R. Lappano, +7 authors V Dolce
  • J. Biol
  • 2012
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…