Hook2 localizes to the centrosome, binds directly to centriolin/CEP110 and contributes to centrosomal function.

@article{Szebenyi2007Hook2LT,
  title={Hook2 localizes to the centrosome, binds directly to centriolin/CEP110 and contributes to centrosomal function.},
  author={Gy{\"o}rgyi Szebenyi and Branden Hall and Rosa Yu and Arig Ibrahim Hashim and Helmut Kr{\"a}mer},
  journal={Traffic},
  year={2007},
  volume={8 1},
  pages={
          32-46
        }
}
Centrosomes serve as microtubule-organizing centers. However, centrosome function depends on microtubule organization and protein transport because the formation, positioning and maintenance of centrosomes require microtubule-dependent retrograde transport. Linker proteins that associate with the motor protein dynein, organelles and microtubules facilitate loading of cargos for retrograde transport and thus contribute to the composition and placement of the centrosome and other juxtanuclear… CONTINUE READING
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