Honokiol and Magnolol Selectively Interact with GABAA Receptor Subtypes in vitro

@article{Ai2001HonokiolAM,
  title={Honokiol and Magnolol Selectively Interact with GABAA Receptor Subtypes in vitro},
  author={J. Ai and Xiaomei Wang and M. Nielsen},
  journal={Pharmacology},
  year={2001},
  volume={63},
  pages={34 - 41}
}
  • J. Ai, Xiaomei Wang, M. Nielsen
  • Published 2001
  • Medicine, Chemistry
  • Pharmacology
Honokiol and magnolol have been identified as modulators of the GABA<sub>A</sub> receptors in vitro. Our previous study suggested a possible selectivity of honokiol and magnolol on GABA<sub>A </sub>receptor subtypes. This possibility was examined in the current study by <sup>3</sup>H-muscimol and <sup>3</sup>H-flunitrazepam binding assays on various rat brain membrane preparations and human recombinant GABA<sub>A</sub> receptor subunit combinations expressed by the Sf-9/baculovirus system… Expand
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