Honey constituents up-regulate detoxification and immunity genes in the western honey bee Apis mellifera.

@article{Mao2013HoneyCU,
  title={Honey constituents up-regulate detoxification and immunity genes in the western honey bee Apis mellifera.},
  author={Wenfu Mao and Mary A. Schuler and May R Berenbaum},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2013},
  volume={110 22},
  pages={8842-6}
}
As a managed pollinator, the honey bee Apis mellifera is critical to the American agricultural enterprise. Recent colony losses have thus raised concerns; possible explanations for bee decline include nutritional deficiencies and exposures to pesticides and pathogens. We determined that constituents found in honey, including p-coumaric acid, pinocembrin, and pinobanksin 5-methyl ether, specifically induce detoxification genes. These inducers are primarily found not in nectar but in pollen in… CONTINUE READING

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