Homozygous deletion in KVLQT1 associated with Jervell and Lange-Nielsen syndrome.

Abstract

BACKGROUND Long-QT (LQT) syndrome is a cardiac disorder that causes syncope, seizures, and sudden death from ventricular arrhythmias, specifically torsade de pointes. Both autosomal dominant LQT (Romano-Ward syndrome) and autosomal recessive LQT (Jervell and Lange-Nielsen syndrome, JLNS) have been reported. Heterozygous mutations in 3 potassium channel… (More)

Topics

2 Figures and Tables

Slides referencing similar topics