Homozygous TRPV1 315C influences the susceptibility to functional dyspepsia.

@article{Tahara2010HomozygousT3,
  title={Homozygous TRPV1 315C influences the susceptibility to functional dyspepsia.},
  author={Tomomitsu Tahara and Tomoyuki Shibata and Masakatsu Nakamura and Hiromi Yamashita and Daisuke Yoshioka and Ichiro Hirata and Tomiyasu Arisawa},
  journal={Journal of clinical gastroenterology},
  year={2010},
  volume={44 1},
  pages={
          e1-7
        }
}
OBJECTIVES Capsaicin/vanilloid (transient receptor potential vanilloid 1, (TRPV1) receptor has been shown to be expressed in gastrointestinal tract and play a role as a member of sensory ion channel superfamily. The G315C polymorphism affects the TRPV1 gene and alters its protein level. We aimed to investigate the effect of TRPV1 G315C polymorphism on functional dyspepsia (FD) in a Japanese population. METHODS TRPV1 G315C polymorphism was genotyped in 98 subjects with no upper abdominal… CONTINUE READING
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