Homozygous Deletion of Six Olfactory Receptor Genes in a Subset of Individuals with Beta-Thalassemia

  title={Homozygous Deletion of Six Olfactory Receptor Genes in a Subset of Individuals with Beta-Thalassemia},
  author={J. van Ziffle and W. Yang and F. Chehab},
  journal={PLoS ONE},
  • J. van Ziffle, W. Yang, F. Chehab
  • Published 2011
  • Biology, Medicine
  • PLoS ONE
  • Progress in the functional studies of human olfactory receptors has been largely hampered by the lack of a reliable experimental model system. Although transgenic approaches in mice could characterize the function of individual olfactory receptors, the presence of over 300 functional genes in the human genome becomes a daunting task. Thus, the characterization of individuals with a genetic susceptibility to altered olfaction coupled with the absence of particular olfactory receptor genes will… CONTINUE READING
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