Homotypic fetal transplants into an experimental model of spinal cord neurodegeneration.

@article{Nothias1990HomotypicFT,
  title={Homotypic fetal transplants into an experimental model of spinal cord neurodegeneration.},
  author={Fatiha Nothias and Marc Peschanski},
  journal={The Journal of comparative neurology},
  year={1990},
  volume={301 4},
  pages={520-34}
}
Many neurotransplantation studies have dealt with the ability of solid fetal spinal grafts to develop in the previously traumatized spinal cord of a host. In neurodegenerative spinal diseases, however, motoneuronal death occurs in the absence of a trauma, i.e., in the absence of axotomy of afferent fibers. Lesioning the spinal cord with an excitotoxic agent may provide a useful neurodegenerative model. The present study has been undertaken to determine whether homotypic fetal neurons… CONTINUE READING