Homophymine A, an anti-HIV cyclodepsipeptide from the sponge Homophymia sp.

@article{Zampella2008HomophymineAA,
  title={Homophymine A, an anti-HIV cyclodepsipeptide from the sponge Homophymia sp.},
  author={Angela Zampella and Valentina Sepe and Paolo Luciano and Filomena Bellotta and Maria Chiara Monti and Maria Valeria D'Auria and Trine Jepsen and Sylvain Petek and M T Adeline and Olivier Lapr{\'e}vote and Anne Marie Aubertin and C{\'e}cile Debitus and Christiane Poupat and Alain Ahond},
  journal={The Journal of organic chemistry},
  year={2008},
  volume={73 14},
  pages={
          5319-27
        }
}
A new anti-HIV cyclodepsipeptide, homophymine A, was isolated from a New Caledonian collection of the marine sponge Homophymia sp. The structure of homophymine A was determined by interpretation of spectroscopic data, acid hydrolysis, and LC-MS analysis. Homophymine A contains 11 amino acid residues and an amide-linked 3-hydroxy-2,4,6-trimethyloctanoic acid moiety. Along with four D-, two L-, and one N-methyl amino acids, it also contains four unusual amino acid residues: (2S,3S,4R)-3,4-diMe… Expand
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References

Chemistry of Lithistid Sponges