Homomeric and heteromeric complexes among TGF-β and BMP receptors and their roles in signaling.

@article{Ehrlich2011HomomericAH,
  title={Homomeric and heteromeric complexes among TGF-β and BMP receptors and their roles in signaling.},
  author={Marcelo Ehrlich and Daniel Horbelt and Barak Marom and Petra Knaus and Yoav I. Henis},
  journal={Cellular signalling},
  year={2011},
  volume={23 9},
  pages={1424-32}
}
Transforming growth factor-β (TGF-β) ligands and bone morphogenetic proteins (BMPs) play myriad roles in many biological processes and diseases. Their pluripotent activities are subject to multiple levels of regulation, including receptor oligomerization, endocytosis, association with co-receptors, cellular scaffolds or membrane domains, as well as transcriptional control. In this review, we focus on TGF-β and BMP receptor homomeric and heteromeric complex formation and their modulation by… CONTINUE READING

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