Homology of lungs and gas bladders: Insights from arterial vasculature

  title={Homology of lungs and gas bladders: Insights from arterial vasculature},
  author={Sarah Longo and Mark L. Riccio and Amy R McCune},
  journal={Journal of Morphology},
Gas bladders of ray‐finned fishes serve a variety of vital functions and are thus an important novelty of most living vertebrates. The gas bladder has long been regarded as an evolutionary modification of lungs. Critical evidence for this hypothesized homology is whether pulmonary arteries supply the gas bladder as well as the lungs. Pulmonary arteries, paired branches of the fourth efferent branchial arteries, deliver blood to the lungs in osteichthyans with functional lungs (lungfishes… 
Lungs and gas bladders: Morphological insights.
Does the bowfin gas bladder represent an intermediate stage during the lung‐to‐gas bladder evolutionary transition?
N nano‐CT scanning is used to visualize the early development of the bowfin gas bladder to verify the historical studies of gas bladder developmental morphology and determine whether the direction ofGas bladder budding in bowfin could be intermediate between ventrally budding lungs and dorsally budding gas bladders.
Pulmonary Transformations of Vertebrates
The discovery of unidirectional airflow in crocodilians and lizards indicates that several inveterate hypotheses for the selective drivers of this trait cannot be correct, and opens an uncharted area for research into selective underpinning of unirrigated airflow.
The vestigial lung of the coelacanth and its implications for understanding pulmonary diversity among vertebrates: new perspectives and open questions
The coelacanth is a key species in addressing this question of lung evolution and for this reason the data recently provided by Cupello and colleagues are a very welcome addition to the discussion.
Changes in Nkx2.1, Sox2, Bmp4, and Bmp16 expression underlying the lung‐to‐gas bladder evolutionary transition in ray‐finned fishes
The genetic underpinnings of this ventral‐to‐dorsal shift in budding direction are investigated by studying the expression patterns of known lung genes during the development of lungs or gas bladder in three fishes: bichir, bowfin, and zebrafish.
The dipnoan buccal pump reconstructed in 3D and implications for air breathing in Devonian lungfishes
3D morphology of Rhinodipterus, a Mid-Late Devonian lungfish from Australia and Europe, based on synchrotron tomography and conventional microtomography scans suggests that it made more extensive use of air breathing than other Gogo or Bergisch Gladbach genera.
A comparative perspective on lung and gill regeneration
  • L. Cádiz, M. Jonz
  • Biology, Environmental Science
    Journal of Experimental Biology
  • 2020
The study of gill regeneration in fish and amphibians, which have a high regenerative potential, represents a unique opportunity to uncover common signaling mechanisms that may be important for regeneration of respiratory organs in all vertebrates.
Evolution, Development, and Function of the Pulmonary Surfactant System in Normal and Perturbed Environments.
The evolutionary origin of the surfactant system, which likely predates lungs, is discussed and an analysis of the ontogeny of surfactants development among the vertebrates and the contribution of different regulatory mechanisms that control this development is presented.
Dorsoventral inversion of the air-filled organ (lungs, gas bladder) in vertebrates: RNAsequencing of laser capture microdissected embryonic tissue.
The genetic basis for the origin of the piscine gas bladder from lungs of ancestral bony vertebrates is investigated and the direction of budding from the foregut during development is distinguished.


The Origin and Evolution of the Surfactant System in Fish: Insights into the Evolution of Lungs and Swim Bladders*
This study presents new data on the surfactant system in swim bladders of three teleost fish and demonstrates the first demonstration of the presence of SP‐D in the air‐breathing organs of nonmammalian species and SP‐B in actinopterygian fishes.
Which came first, the lung or the breath?
Form and Function of Lungs: The Evolution of Air Breathing Mechanisms
Experimental analyses have established that in lower vertebrates lungs are ventilated with a buccal pulse pump, which is driven by identical sets of muscles acting in identical patterns in fishes and frogs, and that respiratory and locomotory patterns are coupled, further maximizing the efficiency of mammalian respiration.
The Evolution of Lung-Gill Bimodal Breathing and the Homology of Vertebrate Respiratory Pumps
A comparative analysis of actinopterygian and sarcoperygian aerial buccal pumps indicates that the primitive pattern of air transfer differs fundamentally between these two clades, suggesting that the independent evolution from different aquatic buCCal pumps may be due to their independent evolution to a single aerialbuccal pump.
Morphology and vascular anatomy of the gills of a primitive air-breathing fish, the bowfin (Amia calva)
  • K. Olson
  • Biology
    Cell and Tissue Research
  • 2004
SummaryThe morphology of the gills of a primitive air breather (Amia calva) was examined by light microscopy of semithin sections of gill filaments, and gill perfusion pathways were identified by
Circulation and respiration in lungfishes (dipnoi)
This paper reviews the cardiorespiratory morphology and physiology of the living lungfishes, in the special context of their highly effective use of both air and water for gas exchange. Particular
Cardiovascular Systems in Primitive Fishes
Chapter 10 – Circulatory System
Expression of a lung developmental cassette in the adult and developing zebrafish swimbladder
This study demonstrates that a suite of genes (Nkx2.1, FoxA2, Wnt7b, GATA6), previously reported to be co‐expressed only in the tetrapod lung, is also co-expressed in the zebrafish swimbladder.
XVI.—Air-Bladder and Lungs: A Contribution to the Morphology of the Air-Bladder of Fish
The theory of an air-bladder origin of the lung was brought forward by Boas, who based his view on purely theoretical arguments, which have not found support in the facts brought to light by the advance of knowledge of the embryology of the more archaic vertebrates.