Homology modeling of opioid receptor-ligand complexes using experimental constraints

Abstract

Opioid receptors interact with a variety of ligands, including endogenous peptides, opiates, and thousands of synthetic compounds with different structural scaffolds. In the absence of experimental structures of opioid receptors, theoretical modeling remains an important tool for structurefunction analysis. The combination of experimental studies and… (More)
DOI: 10.1208/aapsj070243

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