Homology modeling and monoclonal antibody binding of the Der f 7 dust mite allergen.

@article{Shen2011HomologyMA,
  title={Homology modeling and monoclonal antibody binding of the Der f 7 dust mite allergen.},
  author={H D Shen and Ming F. Tam and Chao-Hsien Huang and Hong Nong Chou and Hsiao-Yun Tai and Yu-Sen Chen and Sheh-Yi Sheu and Wayne Robert Thomas},
  journal={Immunology and cell biology},
  year={2011},
  volume={89 2},
  pages={
          225-30
        }
}
The group 7 allergens are important allergenic specificities for mite-sensitive patients and may need to be incorporated into new diagnostic and therapeutic strategies. However, little is known about their biological and structural features. Position-specific iterative BLAST showed that they had strong ancestral homology to two related families of lipid-binding proteins, namely, the bactericidal permeability-increasing (BPI) proteins and the odorant-binding protein. A three-dimensional model of… CONTINUE READING

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