Homology modeling and molecular docking of human pituitary adenylate cyclase-activating polypeptide I receptor

@inproceedings{Wu2014HomologyMA,
  title={Homology modeling and molecular docking of human pituitary adenylate cyclase-activating polypeptide I receptor},
  author={Lusheng Wu and Wenhua Guang and Xiaojia Chen and A. X. Hong},
  booktitle={Molecular medicine reports},
  year={2014}
}
Pituitary adenylate cyclase-activating peptide I receptor (PAC1R) is member of the B class of G protein-coupled seven-transmembrane receptors, with molecular functions associated with neural cell differentiation, regeneration and the inhibition of apoptosis. However, the integrity of the protein structure is difficult to be determined in vitro. In the present study, the physicochemical properties of PAC1R were analyzed, the extracellular, transmembrane and intracellular regions were constructed… CONTINUE READING

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