Homology modeling and in silico prediction of Ulcerative colitis associated polymorphisms of NOD1.

Abstract

Cytosolic pattern recognition receptors play key roles in innate immune response. Nucleotide binding and oligomerisation domain containing protein 1 (NOD1) belonging to the Nod-like receptor C (NLRC) sub-family of Nod-like receptors (NLRs) is important for detection and clearance of intra-cellular Gram negative bacteria. NOD1 is involved in activation of… (More)
DOI: 10.1016/j.mcp.2017.05.009

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