Homologous recombination-mediated double-strand break repair.

  title={Homologous recombination-mediated double-strand break repair.},
  author={C. Wyman and D. Ristic and Roland Kanaar},
  journal={DNA repair},
  volume={3 8-9},
Exchange of DNA strands between homologous DNA molecules via recombination ensures accurate genome duplication and preservation of genome integrity. Biochemical studies have provided insights into the molecular mechanisms by which homologous recombination proteins perform these essential tasks. More recent cell biological experiments are addressing the behavior of homologous recombination proteins in cells. The challenge ahead is to uncover the relationship between the individual biochemical… CONTINUE READING

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