Homologous gene sequences mediate transcription-domain formation.

@article{Binnie2006HomologousGS,
  title={Homologous gene sequences mediate transcription-domain formation.},
  author={Alexandra Binnie and Pedro Castelo-Branco and Joan Monks and Nicholas Proudfoot},
  journal={Journal of cell science},
  year={2006},
  volume={119 Pt 18},
  pages={
          3876-87
        }
}
The organisation of transcription in the mammalian nucleus is a topic of particular interest because of its relevance to gene regulation. RNA polymerase II transcription occurs at hundreds of sites throughout the nucleoplasm. Recent data indicate that coordinately regulated genes can localise to shared transcription sites. Other transcribed sequences have also been shown to cluster in the nucleus. The ribosomal RNA genes cluster in the nucleoli. Similarly, transiently transfected plasmids and… CONTINUE READING

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Exonic tethering of RNA polymerase II transcripts

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