• DOI:10.1038/nrg1614
Corpus ID: 31929047

Homologous chromosome interactions in meiosis: diversity amidst conservation

@article{Gerton2005HomologousCI,
  title={Homologous chromosome interactions in meiosis: diversity amidst conservation},
  author={J. Gerton and R. Hawley},
  journal={Nature Reviews Genetics},
  year={2005},
  volume={6},
  pages={477-487}
}

J. Gerton, R. Hawley

Published 2005

Biology, Medicine

Nature Reviews Genetics

Proper chromosome segregation is crucial for preventing fertility problems, birth defects and cancer. During mitotic cell divisions, sister chromatids separate from each other to opposite poles, resulting in two daughter cells that each have a complete copy of the genome. Meiosis poses a special problem in which homologous chromosomes must first pair and then separate at the first meiotic division before sister chromatids separate at the second meiotic division. So, chromosome interactions… CONTINUE READING

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