Homologous chromosome interactions in meiosis: diversity amidst conservation

  title={Homologous chromosome interactions in meiosis: diversity amidst conservation},
  author={J. Gerton and R. Hawley},
  journal={Nature Reviews Genetics},
  • J. Gerton, R. Hawley
  • Published 2005
  • Biology, Medicine
  • Nature Reviews Genetics
  • Proper chromosome segregation is crucial for preventing fertility problems, birth defects and cancer. During mitotic cell divisions, sister chromatids separate from each other to opposite poles, resulting in two daughter cells that each have a complete copy of the genome. Meiosis poses a special problem in which homologous chromosomes must first pair and then separate at the first meiotic division before sister chromatids separate at the second meiotic division. So, chromosome interactions… CONTINUE READING
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