Homologated amino acids with three vicinal fluorines positioned along the backbone: development of a stereoselective synthesis

Abstract

Backbone-extended amino acids have a variety of potential applications in peptide and protein science, particularly if the geometry of the amino acid is controllable. Here we describe the synthesis of δ-amino acids that contain three vicinal C-F bonds positioned along the backbone. The ultimately successful synthetic approach emerged through the… (More)
DOI: 10.3762/bjoc.13.228

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Cite this paper

@inproceedings{Cheerlavancha2017HomologatedAA, title={Homologated amino acids with three vicinal fluorines positioned along the backbone: development of a stereoselective synthesis}, author={Raju Cheerlavancha and Ahmed Ahmed and Yun Cheuk Leung and Aggie Lawer and Qing-Quan Liu and Marina Cagnes and Hee-Chan Jang and Xiang-Guo Hu and Luke Hunter}, booktitle={Beilstein journal of organic chemistry}, year={2017} }