Homoharringtonine/omacetaxine mepesuccinate: the long and winding road to food and drug administration approval.

@article{Kantarjian2013HomoharringtonineomacetaxineMT,
  title={Homoharringtonine/omacetaxine mepesuccinate: the long and winding road to food and drug administration approval.},
  author={Hagop M Kantarjian and Susan O'brien and Jorge E. Cortes},
  journal={Clinical lymphoma, myeloma & leukemia},
  year={2013},
  volume={13 5},
  pages={530-3}
}
Homoharringtonine/omacetaxine is a unique agent with a long history of research development. It has been recently approved by the Food and Drug Administration for the treatment of chronic myeloid leukemia after failure of 2 or more tyrosine kinase inhibitors. Research with this agent has spanned over 40 years, with many instructive lessons to cancer research, which are summarized in this review. 
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